Archive for March, 2009

Tips to contol your SKIN

Controlling inflammation in your skin can change your skin. 


Inflammation is the Enemy Number #1 to Healthy Skin.  Inflammation breaks down collagen and elastin, increases oil production, and increases the amount of free radicals in the skin. 

Here are a few tips to help control inflammation and keep your skin health.


The normal cleanse, tone, and moisturize is the gold standard but what else can you do?

You have to train your skin to change just like you workout to get your body in better shape your skin needs a workout too.  Here are some tips to keep your skin healthier.


Dry skin:

  1. Water- Drinking water keeps the skin hydrated because throughout the day your skin loses moisture.
  2.  Take a daily Skin, Hair and Nails Vitamin.  Treating your skin topically with quality skin care is great but it is not enough.  You have to treat your skin from the inside too.
  3. Avoid using cleansers and scrubs that dry your skin.
  4. If you live in a dry climate use a humidifier to help keep your skin from drying out.


Oily skin:

  1. Water- Rinse your face with warm water.  Warm water is a better solvent than cold water.
  2. Stress- I know easier said than done but if you can lower your stress level you will be able to control your hormone level that can cause excessive oil secretion.
  3. Use a non-drying mask can help control the oil production.
    1. The problem with most skincare products that “control oil” is that they dry the skin.  Drying oily skin is the worst thing one can do.  If you use a product that dries the skin the body will want to fix the dry skin by producing oil.  The problem is the body can fix the oil skin but the body does not know when to stop.  Example: You cut yourself and the body fixes the cut by growing new skin but the body does not stop at a nice new layer of skin it grows into a scar well the same thing happens with over producing oil.

Pore size reducing ingredients in SKIN1 by Dr Gram clarifying regimen

SKIN1 by Dr Gram clarifying regimen can improve the appearance of pore size due to its anti-septic, anti-inflammatory, soothing and regenerative effect. They purifies and “absorbs” excess oil secretion and makes the pores look smaller.

The key ingredients that reduce pore size are

1. Camphor in SKIN1TM by Dr Gram clarifying mask gently draws out impurities from below the surface, absorbs excess oils helping diminish the appearance of large pores and revitalize skin’s appearance.

2. Witch Hazel in SKIN1TM by Dr Gram clarifying toner reduces pore size by tightening the pore tubule and makes the skin appear smoother.

3. Salicylic acid which is in the entire SKIN1TM by Dr Gram clarifying regimen is a beta hydroxy acid that is oil soluble and is able to seep into the sebum packed pore and exfoliate the dead skin cells that build up inside of the pore. Thus by exfoliating the pore and cleaning out the impurities the pore is not stretched and will shrink back to its normal size.

SKIN1 and Inflammation

Premature aging of the skin and inflammation

Scientists have long known that the root cause of most skin damage is inflammation.  50 years ago, Dr. Denham Harmon first documented the connection between inflammation and skin damage while researching the destructive impact free radicals have on cells.  30 years ago, Kligman and Lavker detailed the role that inflammation plays in visibly aging skin.  More recently, science has identified a link between inflammation and multiple disease states, including heart attacks, colon, skin and prostate cancer, as well as aging of the skin. 

The mechanism of inflammation

There are many factors that can damage the skin:  UV radiation, smoking, excessively aggressive facials, harsh chemicals found in some skincare products, and even hormonal imbalances (for example, in the case of acne).  What most people don’t realize is that all of these agents are related to inflammation of the skin cells.  Irritants such as those above cause disruption of the skin barrier which in turn activates the release of tumor necrosis factor α (TNF) and interleukins 1 (IL1) and 8 (IL-8), as well as other pro-inflammatory molecules to induce protective acute inflammation and trigger repair of the damaged skin barrier.  Matrix metalloproteinases (MMP) are enzymes that activate inflammation and degrade the damaged dermal skin cells like collagen and elastin to remodel the skin after injury.  These destructive enzymes are produced in several skin cells, including fibroblasts, keratinocytes and mast cells.  Collagenase , stromelysin and gelatinase are the most important enzymes in the inflammatory response.  Visible skin aging like fine lines, wrinkles, fragility and laxity are due to solar elastosis, collagen destruction and tissue atrophy induced by damaging MMP activity. 

Thus, the acute inflammatory response plays a vital role in the repair of damaged skin cells.  But the modern woman often faces so much skin stress that chronic inflammation can result.  Here, the body has taken a beneficial reaction too far, and the continual release of destructive enzymes can damage the skin faster than it can repair itself.  The result is premature aging and the possibility of more serious diseases.  

Reversing the damage

For over 100 years, people have used aspirin and other anti-inflammatories to reduce internal inflammation.  And for decades people have taken antioxidant supplements to prevent damage to internal cells.  Now it’s possible to apply the healing properties of both these compounds to the skin as well, reducing current inflammation and preventing its recurrence in the future. 

Any skincare regimen intended to reduce visible skin aging should begin by addressing chronic skin inflammation.  Daily use of a skincare line that fights chronic inflammation will ensure that the skin is functioning at its optimal level of protection.  Dr. Gram has researched the mechanisms of inflammation and the thousands of herbal and antioxidant ingredients available to fight inflammation in topical skincare preparations.  He found that only fourteen of these ingredients have been rigorously tested and clearly shown in human clinical trials to improve skin condition and decrease the visible signs of aging in the skin.  They include, for example, the alpha hydroxy acids that can be found in apples, panax ginseng root extract, green tea, ginger root, retinols from carrots, soy bean extracts, and grape seed extracts.  Dr. Gram has incorporated these proven ingredients to create a new line of skin-care products called SKIN1.  Inflammation has been shown to increase the number of free radicals in the skin, break down collagen and elastin, and increase oil production.  While many lines of skincare products attack free radicals, and anti-aging products seek to heal the damage to collagen and elasting, only SKIN1 does both while also reducing excess oil production by avoiding harsh drying sulfates. 

In addition to SKIN1, Dr. Gram further recommends diet modification along the lines of Andrew Weil’s anti-inflammatory diet.  (Andrew Weil, MD, a leading name in the health field, believes that “without question, diet influences inflammation,” and has formulated a diet especially designed to reduce inflammation.)   


Recent scientific advances have made clear chronic inflammation’s connection to multiple skin conditions, as well as its connection to a host of systemic diseases including cancer.  It is clear that skincare products with the right ingredients can help prevent and reverse chronic inflammation, restoring the skin to its normal condition and helping to minimize, reverse, and/or prevent premature aging of the skin.  Virtually everyone would benefit from a diet rich in anti-inflammatory and antioxidant agents and daily use of topical anti-inflammatory and antioxidant agents such as those found in SKIN1.

SKIN1 by Dr. Gram – First Line to Address Inflammation, Enemy #1 to Healthy Skin

San Diego, CA (March 2009) - Newly launched SKIN1 by Dr. Gram is the first professional line to specifically address chronic inflammation, which research has linked to causing premature aging, skin damage and acne. Compounding pharmacist Dr. Bernard Gramlich utilizes synergies between natural, organic, and pharmaceutical-grade ingredients to prevent chronic inflammation and meet the needs of daily skin maintenance/protection.  It is also the only professional line that is sulfate, paraben and fragrance free.

“Scientific research connected chronic cutaneous inflammation with premature aging and other diseases such as cancer over 50 years ago, so I was surprised to learn this is the first line to control all effects of inflammation,” said Dr. Gramlich.  “Most skin care products have one or two active ingredients in high concentrations which can be extremely harsh – there are 11 active ingredients in every SKIN1 by Dr. Gram product to gently yet effectively treat skin.”

About Inflammation:

The three irritants that disrupt the skin barrier to cause inflammation are: environmental (smoking, allergens, UV rays and pollution); hormonal (stress and acne); and physical (harsh products, medical/cosmetic procedures, and preservatives). Acute inflammation is triggered to repair the damaged skin barrier by remodeling the injured skin. The body does not know when to stop “fixing” itself and continues producing pro-inflammatory molecules to ensure the problem is corrected.  This is chronic inflammation which results in breakdown of collagen elastin, increase in oil production, and an increase in free radicals.  SKIN1 by Dr. Gram is designed to prevent acute inflammation from becoming chronic.

Nutra-VÎt ComplexTM

This signature complex is included in all SKIN1 by Dr. Gram products.  It utilizes the synergies between Niacinamide, glucosamine and two types of Vitamin E to fight inflammation and aging, moisturize, renew DNA, balance skin and slow skin discoloration.

Stem Cell Technology

Eye Rescue is the first skin care product to utilize Rutin, a powerful antioxidant that stabilizes Vitamin C, strengthens collagen elastin and chelates metals from the skin. By reproducing stem cells from Buckwheat, the most powerful source of this ingredient, Dr. Gram has been able to create a natural version that does not oxidize. Microsphere technology effectively delivers Rutin and Vitamin K, a vasal constrictor, to strengthen capillaries to dramatically reduce dark circles and puffiness from under the eye. It includes extra protection from Vitamin C and two forms of Vitamin E, which infuse the skin with unsurpassed antioxidant action and nourishment. The signature Nutra-VÎt ComplexTM works synergistically with botanical extracts to diminish fine lines and wrinkles, while aiding the skin’s natural recovery from environmental damage.

Daily Regimen: Daily Scrub, Daily Cleanser, Daily Moisturizer, Eye Rescue

Daily Scrub contains the powerful action of bamboo, rice brand beads, and walnut shell to

remove the dead surface skin cells that dull a complexion.  It reveals the freshest skin

possible and allows the pure antioxidant and anti-aging properties of Green Tea and Vitamin

E to directly impact the new skin cells.  The signature Nutra-Vît ComplexTM helps balance

hydration, decrease hyperpigmentation, and nourish the complexion.  The blend of organic,

pharmaceutical grade, and natural ingredients work synergistically together to enhance the

skin’s natural resurfacing properties and will invigorate tired dull looking skin.

Acne Regimen: Clarifying Cleanser, Clarifying Toner, Clarifying Mask

Clarifying Mask brings together the antiseptic power of sulfur and camphor with the

soothing relief of oat flour to clear and soothe acne prone skin. This nutrient-rich treatment

purifies and brightens the skin, while minimizing the appearance of pores. Nutra-VÎt

ComplexTM works synergistically with botanical extracts to balance skin hydration and

reduce hyperpigmentation, while aiding the skin’s natural recovery from free radical damage.

Clarifying Cleanser is a non-drying formula designed for all skin types, but especially

beneficial for oily or acne-prone skin.  This deep purifying cleanser uses salicylic acid to

promote healing and preventing of blemishes by removing blackhead-causing bacteria from

the pores while simultaneously exfoliating to decongest the skin. Antioxidants neutralize age

accelerating free radicals while the natural, pharmaceutical grade and organic ingredients

along with the botanicals calm and nourish the skin, leaving the complexion feeling

refreshed and looking radiant.

Environmental Commitment

SKIN1 is committed to being an environmentally conscious company in all aspects of its business, implementing strict recycling guidelines and green eco-packaging.  SKIN1 also only sources ingredients from eco-friendly companies that offer the finest natural, organic and pharmaceutical grade ingredients.
About SKIN1:

As the owner and operator of two successful West Coast pharmacies, Dr. Gramlich has worked with some of the most respected dermatologists in the country. SKIN1 by Dr. Gram merges the finest elements in nature with the most powerful pharmaceuticals to create successful synergies to treat chronic inflammation and common skin care issues without irritation. All products include the signature Nutra-Nutra-VÎt ComplexTM, a combination of anti-oxidants, skin rejuvenators and moisturizers. SKIN1 by Dr. Gram is free from parabens,  sulfates and fragrances, and entirely cruelty-free, Available at and exclusive salons and spas.  For more information visit